Theres no official diet for the heart muscle disease transthyretin amyloid cardiomyopathy (ATTR-CM), but choosing certain foods can help you manage your symptoms and feel your best. Thats because making healthy food choices can help your body maintain the right fluid balance and support heart health overall, saysJohanna Contreras, MD, a cardiologist at Mount Sinai Fuster Heart Hospital in New York City.
These five eating habits can help you get on track. Every persons needs are different, so be sure to check with your cardiology team before making any major changes to your diet.
1. Eat Less Sodium
2. Stay Hydrated
If you have ATTR-CM, youll want to strike a balance with fluid intake. Its important to consume enough liquids to prevent dehydration, but its also important to avoid overhydrating. Depending on the degree of cardiomyopathy, some patients may need to limit how much water they consume in a day, says Dr. Contreras.
Most of your fluids should come from water, since soda andsports drinkssometimes add unnecessary sugar and salt. Water helps maintain hydration without placing additional strain on the heart, Contreras says.
3. Keep an Eye on Your Potassium Intake
4. Limit or Avoid Alcohol
Alcohol can be particularly problematic for ATTR-CM because it can worsen those predisposed to arrhythmias or abnormal heart rhythms, and cause fluid balance disruptions, saysKevin Shah, MD, a cardiologist and the program director for heart failure outreach at MemorialCare Heart & Vascular Institute at Long Beach Medical Center in California. And because alcohol leads to additional urination, it can also lower blood pressure.
I recommend minimizing alcohol consumption or eliminating altogether, says Dr. Shah. Every drink introduces risk that a structurally compromised heart may not be well equipped to handle.
5. Choose Nutrient-Dense Foods and Limit Processed Ones
- Fruits and vegetables
- Whole grains
- Lean proteins like beans, tofu, seafood, and skinless poultry
- Low-fat dairy
- Nuts and seeds
Prioritizing whole foods also leaves less room for ultra-processed foods that are high in sugar, salt, and unhealthy fats, which Contreras says can worsen fluid retention, weight gain, and overall heart health. Limiting these foods can help patients better manage symptoms and avoid additional strain on the heart, she says.
The Takeaway
- While theres no official diet for ATTR-CM, adjusting what you eat can help manage symptoms by supporting heart health and maintaining proper fluid balance.
- Managing fluids and key nutrients is key. People withATTR-CM may need to balance hydration carefully and adjust potassium intake, depending on their diuretic medications, to avoid complications like dehydration and an irregular heart rhythm.
- Focusing on nutrient-dense, minimally processed foods while limiting alcohol can help manage symptoms and prevent added strain on the heart.
Resources We Trust
- Cleveland Clinic: Living With ATTR-CM: Your Questions Answered
- Mayo Clinic: Heart Failure
- American Heart Association: Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
- WomenHeart: What Women Need to Know About ATTR-CM: An Overlooked but Serious Heart Condition
- National Heart, Lung, and Blood Institute: Take Action Toward Better Heart Health
- Heart Failure - Fluids and Diuretics. MedlinePlus. July 14, 2024.
- Tips for Reducing Sodium Intake. Centers for Disease Control and Prevention. March 31, 2026.
- How Salty is Too Salty? A Look at High-Sodium Menu Items. Center for Science in the Public Interest. August 26, 2024.
- Staying Hydrated When You Have Heart Failure. University of Maryland Baltimore Washington Medical Center.
- Griffin JM et al. ATTR Amyloidosis: Current and Emerging Management Strategies. JACC: CardioOncology. October 19, 2021.
- Margolin E et al. Current and Future Treatment Landscape of Transthyretin Amyloid Cardiomyopathy. Cardiology and Therapy. July 19, 2025.
- High Potassium/Low Potassium Diets. American Association of Heart Failure Nurses.
- The Impact of Alcohol Consumption on Cardiovascular Health. World Heart Federation. January 20, 2022.
- Alcohol and Heart Health: Separating Fact from Fiction. Johns Hopkins Medicine.
- Garcia P et al. Nutritional status and its impact on transthyretin cardiac amyloidosis: unraveling connection. European Heart Journal. November 5, 2025.
- Amyloidosis and Nutrition: Eating for Your Health. Amyloidosis Research Consortium. October 26, 2022.
- Living With ATTR-CM: Your Questions Answered. Cleveland Clinic. February 10, 2025.
Chung Yoon, MD
Medical Reviewer
Marygrace Taylor
Author
Marygrace Taylor is an award-winning freelance health and wellness writer with more than 15 years of experience covering topics including womens health, nutrition, chronic conditi...